Job Description

We are seeking a Scientist to lead the development and optimisation of cell-fate engineering approaches for generating retinal cells from alternative somatic cell sources. The successful candidate will design and execute systematic experimental strategies, establish reproducible cell-conversion protocols, and manage a research team to deliver project milestones. The role offers opportunities to translate innovative cell biology into robust processes for future therapeutic development.

Responsibilities

• Lead the development and optimisation of retinal cell-conversion methods using transcription factors, small molecules and/or combination approaches.
• Design and execute systematic screening and optimisation studies covering culture conditions, treatment combinations, dosage and timing.
• Establish quantitative molecular, cellular and functional assays to assess cell identity, conversion efficiency and reproducibility.
• Analyse experimental data, troubleshoot technical challenges and drive evidence-based decisions on subsequent experiments.
• Manage and mentor research staff, coordinate experimental activities, allocate tasks and monitor progress against project milestones.
• Develop standardised protocols, maintain high-quality research documentation, and communicate findings through reports, presentations and scientific outputs.
• Collaborate with multidisciplinary teams to support downstream process development and translation.

Qualifications

Essential Qualifications

• PhD in stem cell biology, developmental biology, cell biology, molecular biology, bioengineering or a related discipline.
• Hands-on experience developing or substantially optimising cell differentiation, reprogramming or cell-fate conversion methods.
• Strong mammalian cell culture and experimental design skills, with experience in relevant molecular or cellular characterisation techniques.
• Demonstrated ability to independently plan experiments, analyse data, troubleshoot and deliver research milestones.
• Ability to supervise or coordinate research staff and communicate effectively within a multidisciplinary team.

Preferred

• Experience in retinal cell biology or differentiation.
• Experience with screening, Design of Experiments (DoE), genetic engineering, transcriptomics or process development.
• Prior experience leading or managing a research team.