Short Description

Immunotherapeutics Biologist

Research Officer / Senior Research Officer

The Therapeutic Antibody Engineering Group at the Singapore Immunology Network (SIgN) is seeking a highly motivated Research Officer or Senior Research Officer to support our biologics drug discovery programs. Our research spans multiple therapeutic areas, including cancer, infectious diseases and inflammatory disorders, with a strong emphasis on translating antibody discoveries into therapeutic candidates.

The successful candidate will contribute to the discovery and preclinical evaluation of human monoclonal antibodies against disease-associated targets. Responsibilities include functional characterization of antibody leads using biochemical and cell-based assays, as well as evaluating therapeutic efficacy in relevant in vivo models. This role offers the opportunity to work with a diverse range of cutting-edge technology platforms within a collaborative, multidisciplinary research environment.

Key Responsibilities

• Design and execute in vitro and in vivo experiments to evaluate therapeutic antibodies.
• Culture and maintain primary cells and mammalian cell lines.
• Develop and perform cell-based functional assays.
• Perform and analyze multicolor flow cytometry experiments.
• Conduct animal studies in accordance with institutional and ethical guidelines.
• Analyze experimental data, prepare reports, and present findings to the research team.
• Collaborate closely with scientists across multidisciplinary projects to advance biologics drug discovery.

Requirements

• Bachelor's degree in Life Sciences, Immunology, Molecular Biology, Biotechnology, or a related discipline.
• Minimum 5 years of hands-on research experience in a biotechnology/pharmaceutical research environment.
• Demonstrated experience in:
  • Primary cell isolation and mammalian cell culture
  • Cell-based functional assays
  • Flow cytometry
  • In vivo animal studies
• Ability to work independently while contributing effectively within a multidisciplinary team.
• Highly motivated, organized, and detail-oriented with strong problem-solving skills.
• Excellent written and verbal communication skills.