Job Description
The A*STAR Institute of Molecular and Cell Biology (IMCB) is inviting applications for a Senior Principal Investigator to lead a research programme in neuroscience, , with particular strengths in neurodegeneration, glial biology, cell fate reprogramming, and translational neuroscience. We seek an internationally recognised scientist with a strong track record in fundamental discovery and translational innovation to develop next-generation therapeutic strategies for neurological disorders. The successful candidate is expected to build a globally competitive programme that contributes to IMCB’s mission of advancing scientific discovery, enabling technology innovation, and supporting Singapore’s growing biotech ecosystem.
Key Responsibilities
- Develop and lead an internationally competitive and independent research programme in neuroscience, with a focus on neurodegeneration, glia-neuron interactions, neural cellular reprogramming, or related areas
- Drive innovative research in molecular and cellular neuroscience, including development of therapeutic strategies for neurological diseases
- Establish translational pipelines spanning target discovery, disease modelling, regenerative medicine, and preclinical validation
- Translate research discoveries into clinical, industrial, or commercial opportunities, including partnerships, and spinoff activities where appropriate
- Secure competitive external funding from national and international agencies
- Mentor and develop a high-performing research team
- Contribute to scientific leadership within IMCB and the broader Singapore biomedical research ecosystem
Qualifications and Requirements
- PhD, MD/PhD, or equivalent in Neuroscience, Molecular Biology, Biomedical Sciences, Regenerative Medicine, or a related discipline
- Strong publication track record in leading peer-reviewed journals such as Cell, Nature, Neuron, Cell Stem Cell or equivalent
- Proven ability to secure substantial competitive funding
- Track record of mentoring and developing successful trainees and junior scientists
- Excellent communication skills and a collaborative mindset