Job Description
Job Title:  Research Officer (HWP Lab), IMCB
Requisition ID:  2476
Posting Start Date:  19/05/2026

Position Overview

We are seeking a highly motivated and detail-oriented Senior Research Officer or Research Officer to support ongoing translational research projects. The successful candidate will play a critical role in driving bench-side execution, focusing on in vivo rodent studies, mammalian cell culture, and standard molecular biology workflows. This role offers excellent opportunities to work within a multidisciplinary team and manage end-to-end experimental data packages.

Key Responsibilities

•    Mouse Colony Management: Manage mouse colony maintenance (breeding, weaning, ear-notching/tagging, and genotyping) and track animal cohorts.
•    Experimental Handling: Perform routine in vivo procedures including dosing (subcutaneous, intraperitoneal, oral gavage) and regular monitoring of body weight, food intake, and overall animal welfare.
•    In-Life & Endpoint Sampling: Assist in executing specific metabolic or functional assessments (e.g., glucose/insulin tolerance tests) and perform terminal tissue collection (blood collection, perfusion, and harvesting/dissection of target organs).
•    In Vitro & Wet Lab Work: Maintain primary or immortalized mammalian cell cultures and execute standard wet-lab assays (RNA/protein extraction, RT-qPCR, Western blotting, and ELISAs).
•    Data & Lab Management: Maintain meticulous and reproducible laboratory notebooks and protocols. Support general lab operations, buffer preparation and reagent stock-taking.

Qualifications & Requirements

Education & Experience
•    Degree: Bachelor’s or Master’s degree in Biological Sciences, Life Sciences, Pharmacology, Biochemistry, or a highly related discipline.
•    Research Experience: Minimum of 6 to 12 months of hands-on laboratory and mouse work experience (prior academic internships, Final Year Projects, or industry attachment counts).


Technical Skills 
•    Essential: Hands-on experience with basic rodent handling and restraint. Competence in basic molecular biology and cellular assays (cell culture, PCR/qPCR, Western blot).
•    Highly Preferred: Direct technical proficiency in basic dosing routes (IP, SC, PO), terminal tissue/blood collection and mouse colony management.
•    Bonus / Advantageous: Prior completion of certified animal care and use courses (e.g., RCULA certification).
o    Experience running specialized metabolic profiling (e.g., GTT/ITT, metabolic chambers) or performing specific surgical models.


Soft Skills
•    Strong organizational discipline with a rigorous approach to experimental controls, reproducibility, and data integrity.
•    Excellent collaborative mindset; capable of multitasking across multiple project streams and coordinating shared resources with other lab members.
•    Strong written and verbal communication skills in English to effectively summarize data for regular lab updates.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.