Description

The lab focuses on therapeutic target discovery and translational development for metabolic dysfunction-associated steatotic liver disease (MASLD), with a strong emphasis on siRNA-based therapeutics.

Our research integrates patient-derived multi-omics datasets with in vivo functional genetic screening and human in vitro disease models to systematically identify and validate clinically relevant therapeutic targets.

Requirements

• Bachelor's or Master's degree in Biomedical Sciences or related fields
• Prior experience in molecular biology and mammalian cell culture
• Experience with hepatocyte models, metabolic disease, or RNA-based techniques is advantageous
• Experience with animal work (mouse handling, injections, tissue collection) is a plus
• Strong organizational and problem-solving skills
• Ability to work independently and collaboratively in a fast-paced environment

Preferred Qualifications (Not Required but Advantageous)

• Experience in liver disease or metabolic disease research
• Experience with siRNA or gene knockdown approaches
• Familiarity with histology or imaging-based assays
• Experience working in translational or interdisciplinary research settings

Interested candidates are invited to send a cover letter stating your research interests and experience, curriculum vitae, and the names and email addresses of three references to LEE Yong-An (Lee_Yong-An@a-star.edu.sg)