Job Description
Job Title:  Principal Investigator, SIgN
Requisition ID:  912
Posting Start Date:  02/04/2026

Job Summary

We are looking for an independent scientist capable of leading a research program in Immunology & Inflammation research, fostering collaborations, securing competitive grants, and contributing to translational outcomes.

Core Competencies (Broad & Non‑Restrictive)

  • Strong expertise in molecular and cellular biology, with experience in genomics or epigenomics‑related approaches.
  • Ability to interpret and integrate NGS datasets (e.g., transcriptional or chromatin profiling such as ChIP‑seq) as part of their research program.
  • Demonstrated track record in securing peer‑reviewed national grants.
  • Experience working within Singapore’s research ecosystem and building multi‑institutional partnerships including with clinical partners.
  • Interest and experience in translating scientific discoveries toward clinical or industry impact (e.g., IP, collaborations, translational grants).

Key Responsibilities

  • Lead an independent research program aligned to the lab’s and institute’s strategic priorities, with flexibility in disease area or biological focus.
  • Develop a sustainable funding pipeline as PI/Co‑PI across basic, clinical, and translational research schemes.
  • Guide research direction and technical strategy, including experimental and/or computational aspects of high‑throughput sequencing workflows.
  • Mentor junior researchers (students, fellows, and research staff) and foster scientific development within the team.
  • Strengthen translational pathways, including IP generation, collaboration with tech‑transfer offices, and engagement with relevant industry or clinical stakeholders.

Requirements

Education & Experience

  • PhD in a relevant Life Science field.
  • Approximately 5–10 years post‑PhD research experience with evidence of independence and leadership.

Technical Strengths

  • Proficiency in molecular biology and functional assays.
  • Experience with genomic or epigenomic techniques (e.g., NGS, transcriptional profiling, chromatin mapping methods).
  • Familiarity with analysis or interpretation of high‑throughput sequencing data (e.g., RNA‑seq, ChIP‑seq, ATAC‑seq).

Additional Skills

  • Strong communication skills for grant writing and stakeholder engagement.
  • Demonstrated ability to collaborate across disciplines, including interactions with clinical partners.
  • Leadership capability and commitment to mentoring.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.