Job Description
Job Title:  [50004074-RSE3A] Senior Scientist I, Computing & Intelligence
Requisition ID:  1485
Posting Start Date:  10/04/2026

Job Summary

About Us
At the Institute of High Performance Computing (IHPC), A*STAR, we drive innovation at the intersection of artificial intelligence and healthcare. Our mission is to build large language models (LLMs), agentic AI and multimodal foundation models that can transform clinical decision support, biomedical discovery, and public health. We are looking for AI Scientist strong applied AI skills ready to build large-scale systems, and you will contribute to innovations that make real impact in healthcare.


Key Responsibilities
•    Research & Development
o    Develop novel architectures, training strategies, and optimization methods for LLMs, agentic AI, vision foundation model and multimodal foundation models.
o    Advance instruction tuning, reinforcement learning (RLHF/GRPO), retrieval-augmented generation (RAG), and knowledge-grounded reasoning in medical AI.
o    Design and implement multimodal learning pipelines that integrate text, imaging, omics, and real-world clinical data.
•    Translation & Collaboration
o    Prototype AI systems for clinical and biomedical applications (e.g., decision support, conversational AI, population health, drug discovery).
o    Benchmark models against state-of-the-art healthcare AI datasets and evaluation frameworks.
o    Collaborate with industry and healthcare partners to enable translation, licensing, and commercialization.
•    Scientific Leadership
o    Publish in top-tier AI/ML venues (e.g., NeurIPS, ICML, ICLR, AAAI, ACL) and high-impact biomedical journals (e.g., Nature Medicine).
o    Contribute to open science initiatives (datasets, model releases, benchmarks).
o    Secure funding through collaborative research proposals with academia, healthcare institutions, and industry.

Qualifications

Minimum Qualifications
•    PhD in Computer Science, Artificial Intelligence, Machine Learning, or related fields.
•    Strong publication record in top AI/ML venues (e.g., NeurIPS, ICML, ICLR, ACL) or high-impact biomedical journals.
•    Deep expertise in LLMs, vision foundation models, or multimodal AI.
•    Strong skills in deep learning frameworks (PyTorch, TensorFlow, JAX) and distributed/HPC training.


Preferred Qualifications
•    Experience in large-scale LLM and/or foundation model training and deployment.
•    Experience with medical or biomedical data (EHR, clinical notes, imaging, genomics).
•    Familiarity with biomedical ontologies and knowledge graphs (UMLS, SNOMED CT, PubMed).
•    Understanding of AI ethics, safety, and regulatory considerations in healthcare.

What We Offer

•    Opportunity to push the frontiers of AI research while delivering real-world healthcare impact.
•    A multidisciplinary environment with leading AI scientists, clinicians, and industry partners.
•    Access to large-scale compute resources and unique biomedical datasets.
•    Support for publications, conference participation, and translational pathways including licensing and spin-offs.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.