Job Description
Job Title:  (Principal) Scientist, Computing & Intelligence, IHPC
Requisition ID:  2609
Posting Start Date:  03/06/2026

Job Summary

Job Description

The Senior AI Research Scientist will be working on clinical multi-agent CDS engineering workstream. The role will design and implement the MAS harness that coordinates GP, pharmacist, specialist, guideline/evidence, medication-safety and workflow agents for primary-care decision support. The system should support pre-consult briefs, iterative re-inference during consultation, safety checks, and structured next-best-action recommendations.

The scientist will be responsible for translating clinical workflow requirements into an executable architecture: agent contracts, orchestration logic, memory/state management, tool interfaces, retrieval layers, evaluation harnesses and observability. The role will also lead simulation-based testing and validation using clinical vignettes, synthetic cases, public benchmarks and protected clinical data pathways where approved.

 

Key Responsibilities

  • Design and implement the MAS/CDS harness, including agent roles, orchestration policies, memory/state handling, tool calling, guardrails and error recovery.
  • Build simulation-based evaluation workflows that generate cases, run multi-agent consultations, compare outputs with labels or clinician review, and record failure modes.
  • Engineer validation pipelines for guideline compliance, medication safety, role adherence, hallucination detection, uncertainty handling, and workflow usability.
  • Integrate clinical foundation models, retrieval components, guideline knowledge bases, structured patient data and clinician feedback loops into a coherent CDS prototype.
  • Lead technical design for pre-consult briefs and iterative consultation support, including re-inference when new patient information, lab results or clinician inputs are added.
  • Collaborate with clinicians, product/workflow teams and evaluation teams to define acceptance criteria, benchmark scenarios, safety thresholds and pilot-readiness evidence.
  • Mentor junior researchers/engineers and establish engineering standards for reproducible MAS experiments, audit trails, dataset versioning and model/system documentation.

 

Required Qualifications and Skills

  • PhD degree in AI, computer science, machine learning, biomedical informatics, computational science or a related field.
  • Strong hands-on experience building LLM applications, agentic systems, orchestration frameworks, evaluation harnesses or production-grade AI research prototypes.
  • Deep understanding of LLM evaluation, retrieval-augmented generation, tool use, safety guardrails, observability, state management and experiment reproducibility.
  • Ability to design validation approaches for clinical AI systems, including synthetic and real-world data evaluation, clinician review workflows and error analysis.
  • Strong software engineering skills in Python and modern AI system stacks; able to convert research ideas into maintainable prototypes and reusable platforms.

 

Preferred Experience

  • Experience with clinical decision support systems, medical LLMs, healthcare workflow integration, FHIR/EMR/eHINTS-like data pathways or regulated AI evaluation.
  • Experience with multi-agent frameworks, simulation environments, LLM-as-judge systems, benchmark construction, or safety testing for high-stakes AI.
  • Knowledge of primary-care chronic disease management and clinical safety issues such as polypharmacy, contraindications, formulary constraints and care-gap detection.
  • Track record leading small technical teams, mentoring junior researchers, and coordinating with clinical, product and governance stakeholders.

The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.