Job Description

• Conduct affinity maturation and enzyme engineering using integrated dry-lab (in silico) and in vitro approaches
• Design and execute selection strategies, including assay development, to support lead asset characterization, prioritization, and optimization
• Perform and analyse protein?protein binding and enzyme kinetics data to guide iterative optimization cycles
• Transitioning to lead proteomics-driven experiments to identify novel biomarkers and validate their therapeutic druggability.
• Prepare presentations, reports, and documentation, support training of junior staff and other assigned research duties

Requirements

• PhD in Protein Engineering, Biochemistry or a related life sciences field
• Experience in binding/kinetic assays, affinity maturation and/or enzyme engineering, computational protein design, sequence analysis and variant prioritization
• Understanding of protein?protein interactions, enzyme kinetics, and developability considerations
• Ability to work collaboratively in interdisciplinary teams and communicate scientific results effectively
• 1-2+ years of postdoc experience in the above areas is a plus